Jul 14, 2025, 15:57

Leukemia & Lymphoma Society Discovery Grant Program

The LLS Discovery Grant Program (formerly Blood Cancer Discoveries Grant Program) funds pioneering early–stage basic research and technological innovation in blood cancer biology. Awards support proof-of-concept studies to elucidate disease mechanisms, develop novel biomarkers, and identify groundbreaking therapeutic targets.

Eligibility Criteria:

Principal Investigator must be an established investigator with > 3 years in an independent faculty appointment at LOI submission.
Open to basic research on blood cancer mechanisms—clonal evolution, autophagy, metabolism, inflammation, DNA damage response, microenvironment/immune interactions, neoantigen discovery, and resistance pathways.
Excludes clinical trials/correlative studies, drug development beyond proof-of-concept, confirmatory/minimally incremental work, research outside blood cancer context, and normal hematopoiesis studies.
Current DGP/BCDG awardees may not apply this cycle.

Funding Details:

Budget: Up to $250,000 USD/year ($750,000 USD total over 3 years), inclusive of indirect costs (capped at 10%).
Funds cover all project-related expenses, including personnel, supplies, equipment, and approved overhead.

Deadline:

Letter of Intent Due: August 19, 2025, 3:00 PM Eastern Time
Call for Proposals Opens: June 30, 2025
Full Application Deadline (invitees only): November 19, 2025, 3:00 PM ET
Notifications: Full-application invites in late September 2025; Awards announced April 2026; Funding begins July 1, 2026.

Where to Go for Further Information:

Download 2025 DGP Guidelines & Instructions and Funding Agreement Template from the LLS Research Portal.
Create or access your account via the LLS Research Portal at research.lls.org.
For technical or program questions, refer to the Guidelines document or contact the LLS Research team via the portal’s helpdesk.