Jul 10, 2025, 08:38

Cancer Center Support Grants for NCI-designated Cancer Centers (P30 Clinical Trial Optional)

This FOA supports P30 Cancer Center Support Grants to fund NCI-designated Cancer Centers—Comprehensive, Clinical, or Basic—that serve as major hubs of transdisciplinary cancer research, develop shared core facilities, fund pilot and developmental projects, engage their catchment communities, coordinate training, and oversee clinical trials.

Eligibility Criteria:

Eligible Organizations
- U.S. institutions of higher education (public or private), non-profits, faith-based or community-based organizations, and certain government entities.
- For New (Type 1) applications: must have ≥ $10 M (Clinical Centers) or ≥ $6 M (Basic Centers) in annual direct-cost cancer-focused NIH funding.
- For Renewal (Type 2) applications: must have ≥ $10 M in annual direct-cost peer-reviewed cancer funding (sum across consortium if approved).
Ineligible
- Foreign (non-U.S.) institutions or foreign components of U.S. organizations.
Applicant Limits
- Only one application per institution (per unique DUNS/IPF).

Funding Details:

Mechanism: P30 Center Core Grant
Project Period: Up to 5 years (with possible 2-year administrative extension to 7 years for meritorious Centers)
Budget: Unrestricted, to cover:
- Central administration and leadership salary support
- Shared Resource operation and management
- Developmental (pilot) project funding
- Community outreach & engagement activities
- Training & education coordination
- Clinical protocol & data management
Clinical Trial Status: Optional (apps may include or omit clinical trial components)

Deadline:

Standard Due Dates Apply (three standard receipt dates each year: February 5, June 5, and October 5)
Expiration Date: January 8, 2026

Where to Go for Further Information:

Full FOA Text: PAR-21-321 on the NIH Grants & Contracts portal
Apply Via: NIH ASSIST or your institution’s S2S solution (see “Apply” button in the FOA)
NCI Office of Cancer Centers.
eRA Commons Registration.
Grants.gov.
Questions: Contact the NCI Office of Cancer Centers Help Desk via the FOA’s Agency Contacts section.