July, 2025
July 2025
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MRA Next Steps Program (MRA)
Jun 27, 2025, 13:58

MRA Next Steps Program (MRA)

The Next Steps program by the Melanoma Research Alliance (MRA) provides milestone-driven funding to bridge preclinical discoveries and clinical translation in melanoma. It supports two priority areas in 2025:

  1. Characterization of Rare Melanoma Preclinical Models

    • Molecular profiling (e.g., multi-omic assays), drug sensitivity/repurposing screens, CRISPR analyses

    • Goal: generate and share well-characterized rare melanoma cell lines, PDX, and models

  2. Advancing Drug Discovery for Acral and Uveal Melanoma

    • Targeted discovery against validated proteins (e.g., CRKL, TERT, GAB2, YAP, Gq/11, LZTR, B7H3)

    • Goal: identify, optimize, and test new therapeutic entities in preclinical models

Eligibility

  • Investigators at academic medical centers or universities worldwide

  • Collaborative teams with expertise in melanoma biology, preclinical modeling, or drug discovery

Funding Details

  • Milestone-based awards: 50,000 – 250,000 USD per project

  • Duration: 1–2 years

  • Applications must include: research proposal, budget, and detailed milestone plan with timeline

RFP Release & Timeline

  • RFP Release: Two separate RFPs to be announced in 2025 on the MRA website and via email

  • Application Deadlines: To be published with each RFP announcement

How to Apply & Contact