Jun 2, 2025, 09:01

Co-infection and Cancer (R01 Clinical Trial Not Allowed)

R01 grants to support in-depth mechanistic and epidemiologic studies of how co-infection with two or more pathogens contributes to cancer initiation, progression, and disparities. Projects should focus on known oncogenic agents (excluding HIV) or co-infections that reveal new prevention or treatment opportunities. Clinical trials are not permitted.

Eligibility

Eligible entities (U.S. & foreign): Higher education institutions; nonprofit and for-profit organizations; local/state governments; tribal organizations; faith-based/community groups; regional entities; non-U.S. entities.
Investigators: Any qualified PD/PI(s) with an eRA Commons account. Multidisciplinary teams (e.g., microbiology, cancer biology, epidemiology) are encouraged.
Project types: R01 mechanism; no clinical trials. Applications must include preliminary data or prior work.

Funding

Mechanism: R01 Research Project Grant (clinical trial not allowed)
Direct costs: No preset cap; budgets must reflect actual project needs. If requesting ≥$500,000/year, contact NCI program staff ≥6 weeks before submission.
Project period: Up to 5 years
Number of awards: Dependent on NIH appropriations and application quality

Key Dates

Posted: November 08, 2024
Open (earliest submission): January 05, 2025
Letter of Intent: 30 days before application due date
Application due (standard NIH dates):
- February 05, 2025, 5 PM local time
- June 05, 2025, 5 PM local time
- October 05, 2025, 5 PM local time
Review & Council:
- February cycle → Review July 2025 → Council October 2025 → Earliest start December 2025
- June cycle → Review November 2025 → Council January 2026 → Earliest start April 2026
- October cycle → Review March 2026 → Council May 2026 → Earliest start July 2026
Expiration: January 08, 2026

Contacts

Epidemiology & general inquiries:
- Tram Kim Lam, Ph.D., M.P.H. | 240-276-6967 | [email protected]
Methods & technologies:
- Rao (Mahesh) Divi, M.D. | 240-276-6913 | [email protected]
Biospecimens:
- Danielle Carrick, Ph.D. | 240-276-6749 | [email protected]
Basic mechanistic studies:
- Phil Daschner, M.S. | 240-276-6227 | [email protected]
- Elizabeth Read-Connole, Ph.D. | 240-276-6190 | [email protected]
Biomarkers, early detection, prevention:
- Jo Ann Rinaudo, Ph.D. | 240-276-7133 | [email protected]
Cancer disparities:
- Anil Wali, Ph.D. | 240-276-6183 | [email protected]
Global health:
- Randiak (James) Alaro, Ph.D. | 240-276-1036 | [email protected]
Imaging:
- Pushpa Tandon, Ph.D. | 240-276-5971 | [email protected]
General Grants Information: [email protected] | 301-480-7075
Grants.gov Support: [email protected] | 800-518-4726