Jun 1, 2025, 17:41

International Research Scientist Development Award (IRSDA) (K01) Independent Clinical Trial Not Allowed

Provides three to five years of mentored research career development support for advanced postdoctoral U.S. research scientists and recently-appointed U.S. junior faculty (at least two years beyond their doctoral degree) to conduct global health research in a low- or middle-income country (LMIC). Applicants may gain experience in clinical trials led by mentors but may not serve as lead investigators on independent trials under this award.

Eligibility Criteria:

U.S. citizens, non-citizen nationals, or permanent residents by the time of award.
Hold a research or health-professional doctoral degree (PhD, MD, DO, DVM, PharmD, etc.) conferred at least two years before application.
Advanced postdoctoral research scientists or junior faculty with research experience beyond doctoral training.
Not current or former PD/PI on NIH R01, P01, P50, D43, major individual K awards (K01, K07, K08, K22, K23, K25, K76, K99/R00) or equivalent non-NIH awards. (R03, R21/R33, R36, SBIR/STTR awardees remain eligible.)
Commit a minimum of 75% full-time professional effort (nine person-months) to the career development program.
Spend at least 50% of cumulative effort—and at least three months per year—in-country at the LMIC research site.
Identify two primary mentors: one at the U.S. institution and one at the collaborating LMIC institution (LMIC mentor must hold a primary appointment at the LMIC site and cannot be a U.S. citizen with joint appointment).
U.S. and LMIC institutions must demonstrate a strong research environment and clear commitment to the candidate’s development.
Applicants proposing to lead an independent clinical trial or ancillary study must apply instead to PAR-24-114.

Funding Details:

Mechanism: K01 Research Scientist Development Award (Non-Clinical Trial)
Award Period: Minimum 3 years; maximum 5 years.
Salary Support: Up to $100,000 per year plus fringe benefits (subject to NIH salary cap).
Research Development Costs: Up to $40,000 per year for supplies, technical personnel, non-degree tuition/registration, statistical/computational services, and travel to research sites/meetings.
Indirect Costs: Reimbursed at 8% of modified total direct costs.
In-Country Requirement: At least 50% effort (all years) and a minimum of three months each year at the LMIC site.
Mentor Support: Mentors must document availability of sufficient research support and facilities.
Budget Justification: Must follow SF424 (R&R) Application Guide and NOFO instructions for all expenses.

Deadline:

All applications are due by 5:00 PM local time of the applicant organization on one of the following dates (expires March 10, 2026):

March 10, 2025 (review July 2025; earliest start December 2025)
March 9, 2026 (review July 2026; earliest start December 2026)

Where to Go for Further Information:

NIH Funding Opportunity Announcement PAR-24-113

cancer career development Fogarty International Center global health International Research Scientist Development Award IRSDA K01 LMIC National Cancer Institute National Eye Institute National Institute on Deafness and Other Communication Disorders NIH OncoDaily Oncology research training

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