May 14, 2025, 09:39

Cancer Grand Challenge: TME Dynamics

This challenge calls for the development of innovative methods to understand the functional and dynamic role of the tumour microenvironment (TME) over time. It seeks to go beyond static spatial mapping and uncover how the TME evolves during tumour development and therapy response, aiming to reshape cancer treatment strategies by preventing resistance and improving outcomes.

Eligibility Criteria:

Open to global, interdisciplinary research teams
Must include expertise in human tumour analysis, spatial genomics/proteomics, AI, computational biology, and functional modelling
Proposals must include longitudinal and functional components and human-based analysis
Pure mapping, animal-only studies, or limited scope proposals will not be considered responsive

Funding Details:

Up to £20 million (USD 25 million) per team
Duration: Not specified

Deadline:

Expressions of Interest due: 18 June 2025

More Information:

Submit your Expression of Interest

cancer cancer resistance cancer therapy immunotherapy resistance longitudinal tumour studies OncoDaily Oncology spatial genomics TME tumour evolution tumour microenvironment

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