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Final pre-spectified overall survival analysis of CLEAR, a phase III study – summarized by Yuksel Urun
Photo from Yuksel Urun/X
Apr 14, 2024, 10:45

Final pre-spectified overall survival analysis of CLEAR, a phase III study – summarized by Yuksel Urun

Yuksel Urun, Professor in Department of Medical Oncology at Ankara University School of Medicine, shared on X:

“Final pre-specified Overall Survival Analysis of CLEAR, a Phase III Study:

  • Final CLEAR trial results: Lenvatinib and Pembrolizumab reduces mortality risk by 21% versus Sunitinib in advanced RCC.
  • While median OS is similar, the combo’s lower HR and tight 95% CI underscore its robust benefit over time.
  • Medians are just midpoints; consistent benefit and CI (Confidence Interval) matter most?

Any insights from the statistical point?”Final pre-spectified overall survival analysis of CLEAR, a phase III study - summarized by Yuksel Urun

Additional information.
Source: Yuksel Urun/X

cancer cancer care Cancer research Clear trial Lenvatinib OncoDaily Oncology pembrolizumab Research sunitinib versus Yüksel Ürün
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