Yitshak Kreiss, is the Director General of Sheba Medical Center at Tel HaShomer, one of the largest and most comprehensive academic medical centers in the Middle East. A physician by training, he completed his medical education at the Hebrew University of Jerusalem and specialized in internal medicine at Sheba. His background spans clinical medicine, health systems management, emergency preparedness, and national health leadership, alongside academic appointments in health administration and medicine.
Under Kreiss’s leadership, Sheba Medical Center has expanded its global standing in clinical excellence, research, and innovation. The institution has been repeatedly recognized among the world’s leading hospitals, reflecting sustained performance across care quality, research, and education. During his tenure, Sheba has advanced its vision as a “City of Health,” accelerating the integration of digital health, artificial intelligence, and translational research into routine care through initiatives such as the ARC innovation ecosystem.
The 100 CEOs featured here reflect the diversity and complexity of modern oncology leadership. In 2025, some lead the world’s largest cancer institutions; others guide specialized societies or emerging innovators. What unites them is responsibility: for millions of patients, for the integrity of science, and for the future direction of cancer care globally.
This list is not a celebration of power, but a recognition of stewardship, accountability, and impact – and of the leaders whose choices continue to shape the fight against cancer. For the many deserving individuals not mentioned in this list, we will continue to acknowledge, honor and elevate your voices in our daily publications from across the world.
See the full list of The 100 Influential CEOs in Oncology in 2025 and stay tuned for other special category nominations
