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Steven Artandi: SCI members find support for ecDNA formation model
Oct 17, 2024, 14:33

Steven Artandi: SCI members find support for ecDNA formation model

Steven Artandi, Director of the Stanford Cancer Institute, shared the following on X:

“Stanford Cancer Institute members Howard Y. Chang, Paul Mischel, and others found support for a model of ecDNA formation in which double-strand break ends dissociate from their legitimate ligation partners prior to joining of illegitimate ends to form the ecDNA and excision scar.”

Steven Artandi: SCI members find support for ecDNA formation model

Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair

Authors: John C. Rose, Julia A. Belk, Ivy Tsz-Lo Wong, Jens Luebeck, Hudson T. Horn, Bence Daniel, Matthew G. Jones, Kathryn E. Yost, King L. Hung, Kevin S. Kolahi, Ellis J. Curtis, Calvin J. Kuo, Vineet Bafna, Paul S. Mischel, Howard Y. Chang

Steven Artandi: SCI members find support for ecDNA formation model

cancer ecDNA Howard Y. Chang OncoDaily Oncology Paul Mischel Research Steven Artandi
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