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Paolo Tarantino: SHR-A1811 x8 +/- pyrotinib vs TCHP for stage III HER2+ early breast cancer
Dec 12, 2024, 20:39

Paolo Tarantino: SHR-A1811 x8 +/- pyrotinib vs TCHP for stage III HER2+ early breast cancer

Paolo Tarantino shared on X:

“Impressive results from a randomized trial of neoadjuvant SHR-A1811 x8 (aka T-DXd cousin) +/- pyrotinib vs TCHP for mostly stage III HER2+ eBC. Comparable pCR rates across arms. Bodes well for DB11, though key differences in the dose and trial design may have relevant impact.”

Paolo Tarantino: SHR-A1811 x8 +/- pyrotinib vs TCHP for stage III HER2+ early breast cancer

Dr. Paolo Tarantino, MD, is pursuing an advanced research fellowship at Dana-Farber Cancer Institute and Harvard Medical School, concurrently working towards a PhD in clinical research at the University of Milan. His research focuses on exploring the HER2 oncoprotein, investigating the emerging HER2-low subgroup of breast tumors, and developing novel antibody-drug conjugates targeting every subtype of breast cancer. With a publication record exceeding 50 papers on breast cancer, he is recognized as a leading expert in the field.