Nihar Desai/X
Feb 1, 2025, 07:30
Nihar Desai: Anemia in CKD
Nihar Desai, Bone Marrow Transplant Physician at Princess Margaret Cancer Center, shared a post on X:
“Anemia in CKD
We all know that CKD = Low EPO
What’s the mechanism? The interstitial cells transdifferentiate into MYOFIBROBLASTS instead of EPO producing cells
Low EPO producing cells = Low EPO = Anemia
It’s not just the Low EPO that causes anemia in patients with CKD
CKD = inflammation = High Hepcidin = Low iron absorption = anemia
Blood loss during dialysis = iron deficiency anemia
CKD = high Uremic toxins = low red cell production.”
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