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Mohit Manrao: The FDA approved AstraZeneca’s NIAGARA regimen in muscle-invasive bladder cancer
Apr 1, 2025, 08:06

Mohit Manrao: The FDA approved AstraZeneca’s NIAGARA regimen in muscle-invasive bladder cancer

Mohit Manrao, SVP, Head of US Oncology at AstraZeneca, shared on LinkedIn:

“This post is intended for a US audience:

Working to extend survival for patients facing tough-to-treat cancers has been the driving force behind our push for new immunotherapy options. The FDA approved AstraZeneca’s NIAGARA regimen in muscle-invasive bladder cancer (MIBC) – confirming that our medicine has the potential to transform outcomes for this patient population.

Chemotherapy plus surgery have long been the standard of care for people with MIBC but nearly 50% face disease recurrence. The NIAGARA trial data unlocked the possibility of longer-term survival with a 32% reduced risk of recurrence and 25% reduced risk of death.

Moving immuno-oncology treatment earlier and attacking tumors from multiple angles is a strategy that we believe will rewrite the future of cancer care. Pushing the boundaries of science, as our team does every day, means that we can deliver powerful results for the MIBC patients we serve.

Read more about the announcement.”