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David Tougeron: Does Prior Sporadic dMMR Primary CRC Increase the Rate of Secondary CRC
Jul 12, 2025, 15:10

David Tougeron: Does Prior Sporadic dMMR Primary CRC Increase the Rate of Secondary CRC

David Tougeron, Professor at Poitiers University Hospital, shared a post on LinkedIn:

“Happy to share the last paper of our digestive Oncology team of Poitiers showing a significant rate of secondary cancers in patients with a prior sporadic dMMR/MSI primary CRC but these cancers are pMMR/MSS (no new dMMR/MSI sporadic tumors due to MLH1 promotor hypermethylation).”

Title: Second malignancies in patients with deficient mismatch repair system/microsatellite instability-high colorectal cancer

Authors: Paul Franques, Pierre Moreau, Camille Evrard, Arnaud Chong-Si-Tsaon, Éric Frouin, Marie-Luce Auriault, Valérie Moulin, Audelaure Junca, Julie Godet, Lucie Lebeau, Roxane Aguillon, Gaëlle Tachon, Lucie Karayan-Tapon, David Tougeron

Read The Full Article at Sage Journals.

David Tougeron: Does Prior Sporadic dMMR Primary CRC Increase the Rate of Secondary CRC

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