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Armando Orlandi: Meta-analysis of 38,050 patients shows topical estrogen during TAM
Armando Orlandi, Medical Oncologist at Agostino Gemelli University Policlinic, posted on X about recent paper by Stavroula L. Kastora et al., titled “Safety of topical estrogen therapy during adjuvant endocrine treatment among patients with breast cancer: A meta-analysis based expert panel discussion” published on Science Direct.
Authors: Stavroula L. Kastora, Eirini Pantiora, Yong Hwa Hong, Meenakshi Veeramani, Hatem A Azim Jr, Rima Chakrabarti, Jürgen Geisler, Ann Knoop, Matteo Lambertini, Barbro Linderholm, Icro Meattini, Ann H Partridge, Ines Vaz-Luis, Denise Vorburger, Gabriella Yongue, Andreas Karakatsanis, Antonios Valachis
Meta-analysis of 38,050 patients shows topical estrogen during TAM is safe, but caution with AI (2.5x recurrence risk).
Mortality doesn’t increase in either case!”
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