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Anirban Maitra: Targeting the PI3Ka-RAS interaction axis
Dec 23, 2024, 06:00

Anirban Maitra: Targeting the PI3Ka-RAS interaction axis

Anirban Maitra, Professor of Pathology and Translational Molecular Pathology at UT MD Anderson Cancer Center shared on X:

“New preprint from Vividion Therapeutics in collaboration with Julian Downward on targeting the PI3Ka-RAS interaction axis, without the collateral effects on compensatory insulin signaling.
Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2.”

Anirban Maitra: Targeting the PI3Ka-RAS interaction axis