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Dan Landau: We developed (scG2P) for targeted co-capture of DNA and mRNA with Mission Bio!

Photo collage of Dan Landau & Mission Bio taken from X

May 27, 2024, 06:45

Dan Landau: We developed (scG2P) for targeted co-capture of DNA and mRNA with Mission Bio!

Dan Landau, Associate Professor at Weill Cornell Medical College, made the following post on X:

“New pre-print!

In collab. with Mission Bio, we developed single-cell Genotype-to-Phenotype (scG2P) for targeted co-capture of DNA & mRNA!

We explore esophagus clonal mosaicism, defining clonal structure the phenotypic impact of somatic drivers.

Dan Landau

These data revealed that clones are biased in their differentiation, showing, in primary human samples, that common drivers (e.g., NOTCH1) support stalled differentiation as driver of clonal outgrowth”

Dan Landau

Read the article.
Source: Dan Landau/X
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Associate Professor cancer clonal outgrowth Dan Landau DNA & mRNA co-capture esophagus clonal mosaicism Mission Bio NOTCH1 OncoDaily Oncology pre-print single-cell Genotype-to-Phenotype (scG2P) somatic drivers Weill Cornell Medical College

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