Angela Toss: Exploratory analysis of BRCA mutations in the MonarchE trial.

Angela Toss, Assistant Professor in the Unit of Genetic Oncology of the Department of Medical and Surgical Sciences at the University of Modena and Reggio Emilia, shared a post on LinkedIn:

“Exploratory analysis of BRCA mutations in the MonarchE trial:

3.5% gBRCA1/2+ (lower than expected)
abema benefit in gBRCA, but not in sBRCA2 and RB1
caution for small sample size

 Do CDK4/6i perform differently in gBRCA early BC patients compared to advanced disease?”

Source: Angela Toss/X