Nina Niu Sanford: A new way to approach radiation toxicity that we term as CUT

Nina Niu Sanford, Assistant Professor of Radiation Oncology at UT Southwestern Medical Center, shared a post on X/Twitter:

“Out now in IJROBP – The Red Journal, my piece with Robert Timmerman describing a new way to approach radiation toxicity that we term as CUT: calculated useful trauma.
In this piece, we draw parallels between surgery & SAbR. We define CUT as the acceptance of essential injury needed to achieve tumor control, so long as that injury occurs in non-vital tissue or heals over time, analogous to surgery.
We argue that with SAbR (as opposed to conventionally fractionated RT), we should be pushing more dose to cover precisely defined tumor targets while devoting greater efforts on techniques aimed to ameliorate normal tissue healing. This was a fun one to write!
In some ways, it is a part 2 to Dr. Timmerman’s famed toxicity tables editorial – definitely worth a read if you haven’t yet.
Thanks to the IJROBP – The Red Journal team for publishing our piece, which is meant to be provocative (I think one of the reviewers described it as “fringe”)”

Source: Nina Niu Sanford/X