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Wafik S. El-Deiry: TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury
Jan 15, 2025, 13:35

Wafik S. El-Deiry: TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury

Wafik S. El-Deiry shared on X:

Pleased to share years of work in online accepted preclinical manuscript with insights, strategies for reducing radiation toxicities that impact patients.

JCI – TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury

Authors: Jillian Strandberg, Anna Louie, Seulki Lee, Marina Hahn, Praveen Srinivasan, Andrew George, Arielle De La Cruz, Leiqing Zhang, Liz Hernandez Borrero, Kelsey E. Huntington, Payton De La Cruz, Attila A. Seyhan, Paul P. Koffer, David E. Wazer, Thomas A. DiPetrillo, Stephanie L. Graff, Christopher G. Azzoli, Sharon I. Rounds, Andres J. Klein-Szanto, Fabio Tavora, Evgeny Yakirevich, Abbas E. Abbas, Lanlan Zhou, and Wafik S. El-Deiry.

Wafik S. El-Deiry: TRAIL agonists rescue mice from radiation-induced lung, skin or esophageal injury

Wafik S. El-Deiry, MD, PhD, FACP, FRSM, is the Associate Dean for Oncologic Sciences at the Warren Alpert Medical School and Director of the Legorreta Cancer Center at Brown University and Director of the Joint Program in Cancer Biology at Brown University and affiliated hospitals. He is the Editor in Chief at Oncotarget. Dr. El-Deiry discovered p21(WAF1) as a p53 target gene, cell cycle inhibitor, and tumor suppressor that explained the mammalian cell stress response. Dr. El-Deiry’s research is focused on mechanisms of therapy resistance with major efforts in drug discovery and development.