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Guilherme Nader Marta: Biomarker analyses of KN-522 shows most markers were prognostic but not predictive
medimix.be
Dec 13, 2024, 16:09

Guilherme Nader Marta: Biomarker analyses of KN-522 shows most markers were prognostic but not predictive

Guilherme Nader Marta, Clinical Fellow at Dana-Farber Cancer Institute, shared a post on X:

“Biomarker analyses of KN-522 shows most markers (T-cell GEP, HRD, HER2 signaling, PTEN, TNBC type) were prognostic but not predictive.

High TMB showed a signal for pembro benefit, but only in 8% of patients.

Predictive biomarkers for ICI in early TNBC are urgently needed.”

Guilherme Nader Marta

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Biomarker analyses biomarkers cancer Guilherme Nader Marta HER2 signaling HRD OncoDaily Oncology patients PTEN T-cell GEP TNBC
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