Vincent Rajkumar: Elephants rarely get cancer. Why?
Vincent Rajkumar, Professor of Medicine at the Mayo Clinic in Rochester, shared a post on X:
“Elephants rarely get cancer. Why?
Mrinal Patnaik explained the reasons at the ECOG-ACRIN Cancer Research Group meeting today.
They have 40 copies of the p53 tumor suppressor gene.
(Humans have 2 copies)”
“Their cells commit suicide at the first hint of abnormality!
Nipping cancer in the bud. Apparently no studies show evidence of visceral cancer in elephants, even on post mortem.”
“Clonal hematopoiesis mutations are highly prevalent and associated with cancer.
But for me the question is can we really do anything about it?
Great talk Mrinal Patnaik.”
Vincent Rajkumar is a Professor of Medicine at the Mayo Clinic in Rochester, Minnesota, and Chair for the Mayo Clinic Myeloma, Amyloidosis, and Dysproteinemia Group. He also chairs the Board of directors of The International Myeloma Foundation and the Eastern Cooperative Oncology Group (ECOG) Myeloma Committee. His extensive contributions include over 230 peer-reviewed publications, predominantly focusing on multiple myeloma and related plasma cell disorders. Furthermore, Dr. Rajkumar is a Section Editor for multiple myeloma and related disorders for Leukemia and an Associate Editor for the Mayo Clinic Proceedings.
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