Amol Akhade: Interlace trial shows OS benefit for advanced cervical cancer

Amol Akhade shared the following on LinkedIn:

“So finally it is published. The much-awaited Interlace trial for locally advanced cervical cancer shows 8% OS benefit at the end of 5 years for neoadjuvant chemo followed by CTRT vs CTRT alone. HR 0.60. Now how will you fit Keynote A18 into this? Pembrolizumab with CTRT did show OS benefit with HR of 0.67. What will you prefer for locally advanced cervical cancer in a patient eligible for both:

1. Interlace – neoadjuvant chemo followed by CTRT

2. Keynote A18 – pembrolizumab plus CTRT

3.Neoadjuvant chemo followed by Pembrolizumab plus CTRT

4.Only CTRT.

do participate in this survey on X
link below.”

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Dr. Amol Akhade is a senior consultant medical oncologist and hemato-oncologist. He has received his super specialization training in hemato-oncology and medical oncology from Tata Memorial Hospital. He specialises in chemotherapy for hematological cancers as well as solid tumors. He also specialises in allogenic and autologous bone marrow transplant. Currently, he is a Consultant Medical Oncologist at Suyog Cancer Clinics and Reliance Hospitals.