Whole-genome Mutational Analysis of CtDNA in Patients with Urothelial Carcinoma – European Urology

European Urology posted on X about recent paper by Iver Nordentoft et al., titled “Whole-genome Mutational Analysis for Tumor-informed Detection of Circulating Tumor DNA in Patients with Urothelial Carcinoma”

Authors: Iver Nordentoft, Sia Viborg Lindskrog, Karin Birkenkamp-Demtröder, Santiago Gonzalez, Maja Kuzman, Jurica Levatic, Dunja Glavas, Ryan Ptashkin, James Smadbeck, Danielle Afterman, Tomer Lauterman, Yarin Cohen, Zohar Donenhirsh, Iman Tavassoly, Ury Alon, Amanda Frydendahl, Mads Heilskov Rasmussen, Claus Lindbjerg Andersen, Philippe Lamy, Michael Knudsen, Paz Polak, Asaf Zviran, Boris Oklander, Mads Agerbæk, Jørgen Bjerggaard Jensen, Lars Dyrskjøt

“Platinum Priority: Whole-genome Mutational Analysis for Tumor-informed Detection of Circulating Tumor DNA in Patients with Urothelial Carcinoma by Iver Nordentoft, Sia Lindskrog et al

Come back later to read the Editorial!”

Markus Eckshteon shared this post on X, adding:

“This is amazing. Congratulations Lars Dyrskjot, who is actually the godfather of ctDNA in urothelial cancer with important studies dating back to 2019. The WGS is very interesting as it is usually easier to perform with low DNA amounts and much cheaper than panel sequencing that is often performed by commercial suppliers like FMI or Natera. Really looking forward to future work of the Aarhus Group, especially from Tombola trial.”