Myeloma Paper of the Day, May 12th, suggested by Robert Orlowski
Robert Orlowski, Director of Myeloma Section at MD Anderson Cancer Center, shared on X:
“Myeloma Paper of the Day: Loss of BCMA expression following TNFRSF17 gene deletions is rare but can occur after any BCMA-directed therapy and prevents response to subsequent anti-BCMA-directed treatments.”
Source: Robert Orlowski/X
Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma
Authors: Ross Firestone, Nicholas Socci, Tala Shekarkhand, Menglei Zhu, Wei Ge Qin, Malin Hultcrantz, Sham Mailankody, Carlyn Rose Tan, Neha Korde, Alexander Lesokhin, Hani Hassoun, Urvi Shah, Kylee Maclachlan, Sridevi Rajeeve, Heather Landau, Michael Scordo, Gunjan Shah, Oscar Lahoud, Sergio Giralt, Kazunori Murata, Saad Usmani, and David Chung.
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