Diego Díaz García Highlights Neuro-Immune Axis in Tumor Growth and Immunity
Diego Díaz García, Medical Oncologist / CEO / Founder at CánCare, shared a post on LinkedIn about a paper by Moran Amit et al. published in Nature:
“Neuro-immune cross-talk in cancer.
The nervous and immune systems share receptors, ligands, and functions that allow direct communication shaping disease and recovery. Emerging evidence highlights how this interplay impacts tumor growth and antitumor immunity.
Peripheral nerve fibers infiltrating tumors can release neuromodulators that influence immune cell behavior and cancer progression. At the same time, tumor-infiltrating immune cells can alter neuronal activity, including nociceptive sensory neurons. Sympathetic signaling adds another layer by driving immunosuppression and T cell exhaustion.
Understanding this neuro-immune axis opens the door to novel strategies aimed at boosting antitumor immunity and improving responses to cancer therapies.
Title: Neuro-immune cross-talk in cancer
Authors: Moran Amit, Tuany Eichwald, Anais Roger, Jennifer Anderson, Aeson Chang, Paola D. Vermeer, Karen O. Dixon, Nicole N. Scheff, Sebastien Talbot
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