Kefah Mokbel: A Real Clinical Entity That Does Not Require Antibiotic Therapy
Kefah Mokbel, Chair of Breast Cancer Surgery at The London Breast Institute, shared a post on LinkedIn:
“Adjuvant chemotherapy recall breast erythema: a real clinical entity that does not require antibiotic therapy
Over the years, I have observed recurrent episodes of breast erythema during successive cycles of adjuvant chemotherapy, occurring in the absence of fever, significant pain, or positive microbiological cultures.
This clinical pattern most likely represents a chemotherapy recall phenomenon at the surgical site, also referred to as a surgical site recall reaction. It is characterized by a localized inflammatory response in previously operated tissue, precipitated by the administration of chemotherapy, and bears a strong resemblance to the well-recognized entity of radiation recall.
Importantly, the patient should be reassured, as this reaction is usually benign and self-limiting. In most cases, it can be managed conservatively with a watch-and-see approach, reserving intervention for instances where signs of infection or systemic involvement develop.”
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