Aug 12, 2025, 19:32
George Kumar: Half a Million Genomes – A Landmark in Precision Medicine
George Kumar, Senior Director at AstraZeneca, shared on LinkedIn:
“Whole-genome sequencing of 490,640 UK Biobank participants
Half a Million Genomes – A Landmark in Precision Medicine
The UK Biobank has completed whole-genome sequencing for 490,640 participants, creating one of the largest and most detailed genomic datasets ever assembled.
- Scale: ~30x coverage per genome, identifying over 1 billion genetic variants
- Depth: Linked with rich clinical, imaging, and lifestyle data
- Discovery: Millions of rare and ultra-rare variants with potential clinical impact
- Global Access: Available to approved researchers worldwide to fuel collaboration
Why it matters:
This milestone will accelerate drug discovery, refine genetic risk prediction, and transform precision medicine – offering new hope for earlier diagnosis, targeted therapies, and improved outcomes.”
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