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Christian Blank: Negative Impact of Stress on Outcome of Checkpoint Inhibition in Melanoma and Lung Cancer
Jul 17, 2025, 22:37

Christian Blank: Negative Impact of Stress on Outcome of Checkpoint Inhibition in Melanoma and Lung Cancer

Christian Blank, Staff Member at The Netherlands Cancer Institute, shared a post on LinkedIn:

“Congratulations Mees Egeler, John Haanen and Lonneke van de Poll-Franse with your tremendously important observation of stress being also relevant for the outcome upon TIL therapy now published in the EJC.

These data are in line with other studies showing the negative impact of stress on outcome of checkpoint inhibition in melanoma and lung cancer. We need to unravel asap the mechanism of action to develop novel combination therapies for the patients with this worse outcome upon immunotherapies.”

Title: The association between pretreatment emotional distress and response to tumor-infiltrating lymphocyte therapy in advanced melanoma

Authors: Mees D. Egeler, Sebastian Klobuch, Willemijn S. Tak, Maartje W. Rohaan, Troels H. Borch, Inge M. Noringriis, Renaud Tissier, Minke W. Lucas, Winan van Houdt, Alexander C.J. van Akkooi, Inge Jedema, Marco Donia, Christian U. Blank, Inge Marie Svane, John B.A.G. Haanen, Lonneke V. van de Poll-Franse

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Christian Blank

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