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Claire Roddie: Check Out How CD19CAR-T for Richter’s Transformation Stacks Up in This UK Analysis

Claire Roddie/vjhemonc.com

Jul 14, 2025, 20:33

Claire Roddie: Check Out How CD19CAR-T for Richter’s Transformation Stacks Up in This UK Analysis

Claire Roddie, Clinician Scientist at UCL, shared a post on X:

“Check out how CD19CAR-T for Richter’s Transformation stacks up in this UK analysis.

Broadly safe and effective, ORR 70%, 2y PFS 46%.

Risks for poor response- high LDH, non-response bridging, more prior lines.”

Title: CD19 chimeric antigen receptor T-cell efficacy and toxicity in adults with Richter’s transformation and response to bridging therapy

Journal: British Journal of Haematology

Authors: Angela Hwang, Amy A. Kirkwood, Maeve O’Reilly, Lorna Neill, Caroline Besley, Shankara Paneesha, Mathew Amrith, Paul Maciocia, Andrea Kuhnl, David Irvine, Jane Norman, Ahmed Abdulgawad, Carlos Gonzalez Arias, Sunil Iyengar, Helen Marr, Satyen Gohil, Claire Roddie

Read the full article.

Richter's Transformation

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Ahmed Abdulgawad Amy A. Kirkwood Andrea Kuhnl Angela Hwang British Journal of Haematology cancer Carlos Gonzalez Arias Caroline Besley CD19CAR-T Claire Roddie David Irvine Helen Marr Jane Norman Lorna Neill Maeve O'Reilly Mathew Amrith OncoDaily Oncology Paul Maciocia Richter's transformation Satyen Gohil Shankara Paneesha Sunil Iyengar

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