Ilyas Sahin shared an article on the mutagenic forces shaping the genomes of lung cancer in never smokers
Ilyas Sahin, Medical Oncologist at Massachusetts General Hospital, shared a post on X:
“Published Nature: Air pollution may drive TP53 and other mutations in lung cancer among never-smokers. EGFR was common in East Asia, KRAS in the West; secondhand smoke showed minimal genomic impact, and herbal toxin–linked signatures were seen in Taiwan.”
Title: The mutagenic forces shaping the genomes of lung cancer in never smokers
Authors: Marcos Díaz-Gay, Tongwu Zhang, Phuc H. Hoang, Charles Leduc, Marina K. Baine, William D. Travis, Lynette M. Sholl, Philippe Joubert, Azhar Khandekar, Wei Zhao, Christopher D. Steele, Burçak Otlu, Shuvro P. Nandi, Raviteja Vangara, Erik N. Bergstrom, Mariya Kazachkova, Oriol Pich, Charles Swanton, Chao Agnes Hsiung, I-Shou Chang, Maria Pik Wong, Kin Chung Leung, Jian Sang, John P. McElderry, Maria Teresa Landi
Read the Full Article.
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