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Filippo Montemurro: Uncovering Actionable Targets in GATA3-Mutant HR+ Resistant Tumors
Jul 6, 2025, 15:32

Filippo Montemurro: Uncovering Actionable Targets in GATA3-Mutant HR+ Resistant Tumors

Filippo Montemurro, Senior Medical Director at Roche, shared a post on X about a paper by Arielle J. Medford et al. published in Breast Cancer Research and Treatment:

“Conoccurring mutations in GATA3 mutant tumors may reveal actionable targets in HR+ resistant tumors. Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes – PubMed.”

Title: Genomic and proteomic profiling of GATA3 mutant metastatic hormone receptor-positive breast cancer and impact on clinical outcomes

Authors: Arielle J. Medford, Marko Velimirovic, Yifat Gefen, Andrzej Niemierko, Lorenzo Gerratana, Andrew A. Davis, Katherine Clifton, Jennifer Keenan, Emily Podany, Whitney L. Hensing, Carolina Reduzzi, Charles S. Dai, Lesli A. Kiedrowski, Laura M. Spring, Leif W. Ellisen, Robert C. Doebele, Massimo Cristofanilli, Gad Getz, Aditya Bardia

You can read the Full Article in Breast Cancer Research and Treatment.

Filippo Montemurro: Uncovering Actionable Targets in GATA3-Mutant HR+ Resistant Tumors

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