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Jason Westin: Mosun-Pola Is Superior to Chemotherapy for Patients with Aggressive Lymphoma
Jun 23, 2025, 06:59

Jason Westin: Mosun-Pola Is Superior to Chemotherapy for Patients with Aggressive Lymphoma

Jason Westin, Lead of the Lymphoma and Myeloma Service Line at MD Anderson Cancer Center, shared a post on LinkedIn:

“Big news from the 2025 International Conference on Malignant Lymphoma (ICML): Mosun-Pola is superior to chemotherapy for patients with aggressive lymphoma.
At the ICML meeting, I was honored to present, on behalf of an incredible team of global coauthors, the results of the Phase III SUNMO trial:
  • First positive Phase III trial in this space without conventional chemotherapy
  • 59% reduction in risk of progression or death
  • Tripled median PFS
  • Doubled CR rate
Importantly, Mosun-Pola has the lowest CRS incidence and severity reported to date for a T-cell–engaging therapy:
  • 96% of patients had no significant CRS
  • Fixed-duration, outpatient regimen
  • Combines a bispecific antibody with an ADC
This may open the door for broader patient access and outpatient delivery at more centers—helping more people with refractory or relapsed transplant-ineligible large B-cell lymphoma.
Excited for what’s ahead!”

Jason Westin: Mosun-Pola Is Superior to Chemotherapy for Patients with Aggressive Lymphoma

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