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Phase 1 data from the auristatin HER2 ADC PF-06804103 highlight the importance of optimizing the toxicity profile of novel ADCs – Paolo Tarantino
Jul 9, 2023, 09:59

Phase 1 data from the auristatin HER2 ADC PF-06804103 highlight the importance of optimizing the toxicity profile of novel ADCs – Paolo Tarantino

Phase 1 data from the auristatin HER2 ADC PF-06804103 highlight the importance of optimizing the toxicity profile of novel ADCs. The drug showed relevant activity (ORR 30%) for HER2+ BC & GC, but nearly half of the pts discontinued treatment for toxicity.

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Source: Paolo Tarantino/Twitter