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Paolo Tarantino: LAG3 blockade adds upon PD1 blockade in melanoma
Dec 17, 2024, 01:16

Paolo Tarantino: LAG3 blockade adds upon PD1 blockade in melanoma

Paolo Tarantino, Advanced Research Fellow at Dana-Farber Cancer Institute, shared a post by Akhil Santhosh,  at  on X:

“LAG3 blockade clearly adds upon PD1 blockade in melanoma, with 20% reduction in the risk of death.

Could it also improve outcomes in other cancer types?”

Quoting Akhil Santhosh’s post:

The 3-year results of relativity 047 out in Journal of Clinical Oncology.

Nivolumab and relatlimab continues to impress. Toxicity profile better than nivo ipi. Interestingly, at the 3 year follow up, upper bound of HR 95% ci is less than 1 for overall survival.”

“Three-Year Overall Survival With Nivolumab Plus Relatlimab in Advanced Melanoma From RELATIVITY-047”

Authors: Hussein Tawbi et al.

Paolo Tarantino: LAG3 blockade adds upon PD1 blockade in melanoma

More posts featuring Paolo Tarantino.

Dr. Paolo Tarantino, MD, is pursuing an advanced research fellowship at Dana-Farber Cancer Institute and Harvard Medical School, concurrently working towards a PhD in clinical research at the University of Milan.

His research focuses on exploring the HER2 oncoprotein, investigating the emerging HER2-low subgroup of breast tumors, and developing novel antibody-drug conjugates targeting every subtype of breast cancer. With a publication record exceeding 50 papers on breast cancer, he is recognized as a leading expert in the field.