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The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute
Nov 10, 2024, 13:41

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Dana-Farber’s Breast Oncology Center shared on X:

“Check out the Breast Cancer Research Digest – a summary of last week’s publications from select high-impact journals (October 28th-November 3rd, 2024).”

Pathologic complete response (pCR) rates for patients with HR+/HER2- high-risk, early-stage breast cancer (EBC) by clinical and molecular features in the phase II I-SPY2 clinical trial

Authors: L A Huppert, D Wolf, C Yau, L Brown-Swigart, G L Hirst, C Isaacs, L Pusztai, P R Pohlmann, A DeMichele, R Shatsky, D Yee, A Thomas, R Nanda, J Perlmutter, D Heditsian, N Hylton, F Symmans, L J van ‘t Veer, L Esserman, H S Rugo

Breast Cancer

Adding Metastasis-Directed Therapy to Standard-of-Care Systemic Therapy for Oligometastatic Breast Cancer (EXTEND): a Multicenter, Randomized Phase II Trial

Authors: Jay P Reddy, Alexander D Sherry, Bryan Fellman, Suyu Liu, Tharakeswara Bathala, Cara Haymaker, Lorenzo Cohen, Benjamin D Smith, David Ramirez, Simona F Shaitelman, Stephen G Chun, Marina Medina-Rosales, Mediget Teshome, Abenaa Brewster, Carlos H Barcenas, Alexandre Reuben, Amol J Ghia, Ethan B Ludmir, Daniel Weed, Shalin J Shah, Melissa P Mitchell, Wendy A Woodward, Daniel R Gomez, Chad Tang

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Effects of a culturally tailored patient navigation program on unmet supportive care needs in Hispanic/Latino cancer survivors: A randomized controlled trial

Authors: Blanca S Noriega Esquives, Patricia I Moreno, Edgar Munoz, Thomas E Lad, Courtney M P Hollowell, Roberto M Benzo, Amelie G Ramirez, Frank J Penedo

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Camizestrant, a next-generation oral SERD, versus fulvestrant in post-menopausal women with oestrogen receptor-positive, HER2-negative advanced breast cancer (SERENA-2): a multi-dose, open-label, randomised, phase 2 trial

Authors: Mafalda Oliveira, Denys Pominchuk,Zbigniew Nowecki, Erika Hamilton, Yaroslav Kulyaba, Timur Andabekov, Yevhen Hotko, Tamar Melkadze, Gia Nemsadze, Patrick Neven, Vladimir Vladimirov, Claudio Zamagni, Hannelore Denys, Frédéric Forget, Zsolt Horvath, Alfiya Nesterova, Maxine Ajimi, Bistra Kirova, Teresa Klinowska, Justin P O Lindemann, Delphine Lissa, Alastair Mathewson, Christopher J Morrow, Zuzana Traugottova, Ruaan van Zyl, Ekaterine Arkania

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer

Authors: Stav Rabani, Emine Gulsen Gunes, Martin Gunes, Bianca Pellegrino, Bar Lampert, Keren David, Raju Pillai, Aimin Li, Shirly Becker-Herman, Steven T Rosen, Idit Shachar 

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors

Authors: Xiaowei Bian, Minna Piipponen, Zhuang Liu, Lihua Luo, Jennifer Geara, Yongjian Chen, Traimate Sangsuwan, Monica Maselli, Candice Diaz, Connor A Bain, Evelien Eenjes, Maria Genander, Michael Crichton, Jenna L Cas, Louis Archambault, Siamak Haghdoost, Julie Fradette, Pehr Sommar, Martin Halle, Ning Xu Landén

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Invasive disease-free survival and brain metastasis rates in patients treated with neoadjuvant chemotherapy with trastuzumab and pertuzumab

Authors: S M Chew, E Ferraro, Y Chen, A V Barrio, D Kelly, S Modi, A D Seidman, H Wen, E Brogi, M Robson, C T Dang

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Immune checkpoint inhibitors for patients with metastatic triple-negative inflammatory breast cancer (INCORPORATE): An international cohort study

Authors: Carmine Valenza, Dario Trapani, Paola Zagami, Gabriele Antonarelli, Luca Boscolo Bielo, Eleonora Nicolò, Joana Mourato Ribeiro, Lorenzo Guidi, Carolina Reduzzi, Martina Spotti, Laura Adamoli, Javier Cortès, Barbara Pistilli, Sara M Tolaney, Naoto Ueno, Rachel M Layman, Massimo Cristofanilli, Lisa A Carey, Elisabetta Munzone, Carmen Criscitiello, Filipa Lynce, Wendy A Woodward, Giuseppe Curigliano

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Outcomes of patients treated with chemotherapy for breast cancer during pregnancy compared with nonpregnant breast cancer patients treated with systemic therapy

Authors: Helen M Johnson, Juhee Song, Carla L Warneke, Ashley L Martinez, Jennifer K Litton, Oluchi C Oke

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Second Primary Cancer Risks After Breast Cancer in BRCA1 and BRCA2 Pathogenic Variant Carriers

Authors: Isaac Allen, Hend Hassan, Yvonne Walburga, Catherine Huntley, Lucy Loong, Tameera Rahman, Sophie Allen, Alice Garrett, Bethany Torr,Andrew Bacon, Craig Knott, Sophie Jose, Sally Vernon, Margreet Lüchtenborg, Joanna Pethick, Francesco Santaniello, Shilpi Goel, Ying-Wen Wang, Katrina Lavelle, Fiona McRonald, Diana Eccles, Eva Morris, Steven Hardy, Clare Turnbull, Marc Tischkowitz, Paul Pharoah, Antonis C Antoniou

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer using a machine learning approach

Authors: Fangyuan Zhao, Eric Polley, Julian McClellan, Frederick Howard, Olufunmilayo I. Olopade and Dezheng Huo

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer

Authors: Susrutha Puthanmadhom Narayanan, Abdalla M Wedn, Osama Shiraz Shah, Jian Chen, Daniel D Brown, Priscilla F McAuliffe, Steffi Oesterreich, Adrian V Lee

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Contribution of health insurance to racial and ethnic disparities in advanced stage diagnosis of 10 cancers

Authors: Parichoy Pal Choudhury, Helmneh M Sineshaw, Rachel A Freedman, Michael T Halpern, Leticia Nogueira, Ahmedin Jemal, Farhad Islami

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features

Authors: Johanna Klughammer, Daniel L Abravanel, Åsa Segerstolpe, Timothy R Blosser, Yury Goltsev , Yi Cui, Daniel R Goodwin, Anubhav Sinha, Orr Ashenberg, Michal Slyper, Sébastien Vigneau, Judit Jané-Valbuena, Shahar Alon, Chiara Caraccio, Judy Chen, Ofir Cohen, Nicole Cullen, Laura K DelloStritto, Danielle Dionne, Janet Files, Allison Frangieh, Karla Helvie, Melissa E Hughes, Stephanie Inga, Abhay Kanodia, Ana Lako, Colin MacKichan, Simon Mages, Noa Moriel, Evan Murray, Sara Napolitano, Kyleen Nguyen, Mor Nitzan, Rebecca Ortiz, Miraj Patel, Kathleen L Pfaff, Caroline B M Porter, Asaf Rotem, Sarah Strauss, Robert Strasser, Aaron R Thorner, Madison Turner , Isaac Wakiro, Julia Waldman, Jingyi Wu, Jorge Gómez Tejeda Zañudo, Diane Zhang, Nancy U Lin, Sara M Tolaney, Eric P Winer, Edward S Boyden, Fei Chen, Garry P Nolan, Scott J Rodig, Xiaowei Zhuang, Orit Rozenblatt-Rosen, Bruce E Johnson, Aviv Regev, Nikhil Wagle

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages

Authors: Michael D Iglesia, Reyka G Jayasinghe, Siqi Chen, Nadezhda V Terekhanova, John M Herndon, Erik Storrs, Alla Karpova, Daniel Cui Zhou, Nataly Naser Al Deen, Andrew T Shinkle, Rita Jui-Hsien Lu, Wagma Caravan, Andrew Houston, Yanyan Zhao, Kazuhito Sato, Preet Lal, Cherease Street, Fernanda Martins Rodrigues, Austin N Southard-Smith, André Luiz N Targino da Costa, Houxiang Zhu, Chia-Kuei Mo, Lisa Crowson, Robert S Fulton, Matthew A Wyczalkowski, Catrina C Fronick, Lucinda A Fulton, Hua Sun, Sherri R Davies, Elizabeth L Appelbaum, Sara E Chasnoff, Madelyn Carmody, Candace Brooks, Ruiyang Liu, Michael C Wendl, Clara Oh, Diane Bender, Carlos Cruchaga, Oscar Harari, Andrea Bredemeyer, Kory Lavine, Ron Bose, Julie Margenthaler, Jason M Held, Samuel Achilefu, Foluso Ademuyiwa, Rebecca Aft, Cynthia Ma, Graham A Colditz, Tao Ju, Stephen T Oh, James Fitzpatrick, E Shelley Hwang, Kooresh I Shoghi, Milan G Chheda, Deborah J Veis, Feng Chen, Ryan C Fields, William E Gillanders, Li Ding

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Supplemental breast cancer screening after negative mammography in U.S. women with dense breasts

Authors: Victoria M Foster, Amy Trentham-Dietz, Natasha K Stout, Christoph I Lee, Laura E Ichikawa, Joanna Eavey, Louise Henderson, Diana L Miglioretti, Anna N A Tosteson, Erin A Bowles, Karla Kerlikowske, Brian L SpragueThe most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Combined analysis of the MF18-02/MF18-03 NEOSENTITURK studies: ypN-positive disease does not necessitate axillary lymph node dissection in patients with breast cancer with a good response to neoadjuvant chemotherapy as long as radiotherapy is provided

Authors: Mahmut Muslumanoglu, Neslihan Cabioglu, Abdullah Igci, Hasan Karanlık, Havva Belma Kocer, Kazim Senol, Baris Mantoglu, Mustafa Tukenmez, Guldeniz Karadeniz Çakmak, Enver Ozkurt, Mehmet Ali Gulcelik, Selman Emiroglu, Baran Mollavelioglu, Nilufer Yildirim, Suleyman Bademler, Baha Zengel, Didem Can Trabulus, Mustafa Umit Ugurlu, Cihan Uras, Serkan Ilgun, Gokhan Giray Akgul, Alper Akcan, Serdar Yormaz, Yeliz Emine Ersoy, Serdar Ozbas, Ece Dilege, Bulent Citgez, Yasemin Bolukbasi, Ayse Altınok, Ahmet Dag, Gül Basaran, Nihat Zafer Utkan, Beyza Ozcinar, Cumhur Arici, Israa AlJorani, Halil Kara, Banu Yigit, Ebru Sen, Fazilet Erozgen, Aykut Soyder, Burak Celik, Halime Gul Kilic, Leyla Zer, Gürhan Sakman, Levent Yeniay, Kemal Atahan, Ecenur Varol, Vefa Veliyeva, Berk Goktepe, Mehmet Velidedeoglu, Niyazi Karaman, Atilla Soran, Adnan Aydiner, Ravza Yılmaz, Kamuran Ibis, Vahit Ozmen

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels

Authors: Saptarshi Sinha, Brennan W Callow, Alex P Farfel, Suchismita Roy, Siyi Chen, Maria Masotti, Shrila Rajendran, Johanna M Buschhaus, Celia R Espinoza, Kathryn E Luker, Pradipta Ghosh, Gary D Luker

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Inavolisib-Based Therapy in PIK3CA-Mutated Advanced Breast Cancer

Authors: Nicholas C Turner, Seock-Ah Im, Cristina Saura, Dejan Juric, Sibylle Loibl, Kevin Kalinsky, Peter Schmid, Sherene Loi, Patrapim Sunpaweravong, Antonino Musolino, Huiping Li, Qingyuan Zhang, Zbigniew Nowecki, Roland Leung, Eirini Thanopoulou, Noopur Shankar, Guiyuan Lei, Thomas J Stout, Katherine E Hutchinson, Jennifer L Schutzman, Chunyan Song, Komal L Jhaveri

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Metabolic syndrome and risks of breast cancer outcomes for luminal, triple-negative, and HER2-overexpressing subtypes

Authors: Nicole C Loroña, Megan Othus, Kathleen E Malone,Hannah M Linden, Mei-Tzu C Tang, Christopher I Li

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Prediction of breast cancer risk for adolescents and young adults with Hodgkin lymphoma

Authors: Sander Roberti, Flora E van Leeuwen, Ibrahima Diallo, Florent de Vathaire, Michael Schaapveld, Wendy M Leisenring, Rebecca M Howell, Gregory T Armstrong, Chaya S Moskowitz, Susan A Smith, Berthe M P Aleman, Inge M Krul, Nicola S Russell, Ruth M Pfeiffer, Michael Hauptmann

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

Ischaemic cardiotoxicity of aromatase inhibitors in postmenopausal patients with early breast cancer in Denmark: a cohort study of real-world data

Authors: Marie Lund, Giulia Corn, Maj-Britt Jensen, Tonny Petersen, Kim Dalhoff, Bent Ejlertsen, Lars Køber, Jan Wohlfahrt, Mads Melbye

The most recent Breast Cancer Research Digest by Dana-Farber Cancer Institute

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