Aaron Goodman: One of my favorite differentials, Intestinal T/NK lymphoma

Aaron Goodman, Associate Professor of Medicine at the University of California, San Diego, shared a post on X:

“One of my favorite differentials!
Intestinal T/NK lymphoma!

Can be very aggressive or very indolent!

Let the clinical scenario guide you!
If incidental on screening colonoscopy please don’t blast with chemotherapy.

Aggressive: EATL = Refractory celiac
MEITL = Like EATL, no celiac

Indolent:

IT-LPD:

CD4,CD8 types
JAK-STAT
Slight risk transformation

NK-enteropathy:

CD56+
JAK3

A must have image for T-cell lymphoma enthusiasts [Jaffe. Haematol.20]”

Aaron Goodman is a Hematologist/ Oncologist and an Associate Professor of Medicine at the University of California, San Diego. He is a member of the National Comprehensive Cancer Network (NCCN) guideline committee for both cutaneous NHLs and T-cell NHLs. Dr. Goodman is a well-known physician-scientist, educator, advocate, and social media influencer.