Erman Akkus: Neoadjuvant CRT vs. ChT for initially unresectable locally advanced ‘Colon’ cancer

Erman Akkus posted on X:

“Neoadjuvant CRT vs. ChT for initially unresectable locally advanced ‘Colon’ cancer.

• 45 patients.
• R0 resection: 80% vs. 20%, P < 0.001.
• 3-year PFS: 76% vs. 45% , P = 0.049.
• 3-year OS: 87.6% vs. 75% , P = 0.037.
• No differences in severe AEs.

Study was terminated prematurely because of R0 resection benefit of CRT.”

Source: Erman Akkus/X

Neoadjuvant chemoradiotherapy versus neoadjuvant chemotherapy for initially unresectable locally advanced colon cancer: short-term outcomes of an open-label, single-centre, randomised, controlled, phase 3 trial

Authors: Zi-Tong Zhang, Wei-Wei Xiao, Li-Ren Li, Xiao-Jun Wu, Qiao-Xuan Wang, Hui Chang, Xue Tian, Wu Jiang, Jun-Zhong Lin, Rong-Xin Zhang, Wen-Hua Fan, Zhi-Zhong Pan, Rong Zhang, and Yuan-Hong Gao.

Erman Akkus is a medical oncology fellow at the Ankara University, Faculty of Medicine. Previously, he was an Internal Medicine Resident at the Ankara University, Faculty of Medicine. He was also a Visiting Researcher at the University of Oslo. He completed his education from the Medical University of Vienna.