News Feed Opinion Blog Career Insight Dialogues Celebrities Oncolibrary
Positive Societies Drugs Stories History Cancer Center Near Me Cancer Types Immune Oncology Oncologist Near Me
May, 2025
May 2025
M T W T F S S
 1234
567891011
12131415161718
19202122232425
262728293031  
Ana Velázquez Mañana highlights NEJM study by John Heymach on Zongertinib’s efficacy in HER2-Mutant NSCLC at AACR25
Ana Velázquez Mañana and John Heymach
May 1, 2025, 17:14

Ana Velázquez Mañana highlights NEJM study by John Heymach on Zongertinib’s efficacy in HER2-Mutant NSCLC at AACR25

Ana Velázquez Mañana, shared a post on X, about a recent article by John Heymach et al. published in NEJM, adding:

“Lung Cancer Clinical Trials at AACR25!
Zongertinib in pretreated HER2 mutant NSCLC: Beamion LUNG-1
– ORR 71% (7% CR) with mDOR 14.1 mo
– mPFS 12.4 mo (95% CI, 8.2 to NR)
– Intracranial ORR 41%
– Pretx with HER2 ADC (cohort 5; n=31) ORR 48%
– Improved AE profile compared to prior TKIs and NO ILD reported.
– Active also in non-TKD mut.
By Dr. John Heymach, MD Anderson Cancer
Publication in NEJM.”

Ana Velázquez Mañana

Zongertinib in Previously Treated HER2-Mutant Non–Small-Cell Lung Cancer

Authors: John Heymach et al.

Ana Velázquez Mañana

More posts featuring Ana Velázquez Mañana on OncoDaily.

AACR25 Beamion LUNG-1 Behbood Sadrolhefazi Byoung Chul Cho cancer David Planchard Egbert F. Smit Ernest Nadal Gerrina Ruiter Hai-Yan Tu HER2 mutant NSCLC John Heymach Jon Zugazagoitia Joshua K. Sabari Kiyotaka Yoh Lung cancer Maren Rohrbacher MD Anderson Cancer Myung-Ju Ahn NEJM Nicolas Girard Noboru Yamamoto NSCLC OncoDaily Oncology Sabina Eigenbrod-Giese Ute von Wangenheim Yanqiu Zhao Yi-Long Wu Zongertinib
Special Coverage
Science
May 1, 2025, 17:14
Ana Velázquez Mañana highlights NEJM study by John Heymach on Zongertinib’s efficacy in HER2-Mutant NSCLC at AACR25
Blog
May 1, 2025, 17:09
Aynur Aktas: Our Abstract Has Been Selected for Oral Presentation at MASCC 2025
Insight
May 1, 2025, 17:01
Ken Cardona leads EA7211/STRASS 2 clinical trial: A randomized study in retroperitoneal sarcoma - ECOG-ACRIN Cancer Research Group
Blog
May 1, 2025, 16:54
Phnom Penh Launches Cancer Care Projects to Strengthen Services - City Cancer Challenge
Blog
May 1, 2025, 16:49
SHRO honors three medical students from the University of Siena for completing U.S. research program
Blog
May 1, 2025, 16:46
MedAccess and Elekta Partner to Launch Pay-Per-Use Radiotherapy Model for Cancer Care in LMICs
Blog
May 1, 2025, 16:38
Wade Swenson: Registration is now open for the 2025 Rural Oncology Conference
Insight
May 1, 2025, 16:36
Drew Moghanaki: CW pain is rare, and when it occurs always heals
Positive
May 1, 2025, 16:33
Paula Bos: Superstar Undergraduate from VCU Massey Cancer Center Presents Research at AACR2025
Blog
May 1, 2025, 16:32
Rachel Chown: From Manchester Monday to Tim Tuesday at AACR25
Blog
May 1, 2025, 16:31
POEM 4th Scientific Meeting continues with insightful sessions on data metrics and analysis
Blog
May 1, 2025, 16:22
NIH Decision to Restrict Data Access Hinders Global Cooperation - Fight Colorectal Cancer