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Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 – 21
Feb 25, 2025, 09:48

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 – 21

Dana-Farber Lank Center for Genitourinary Oncology shared a post on X:

“GU Research Digest for the week of February 15 – 21: a selection of publications about GU cancers in high-impact journals. Search the PMIDs on PubMed to read!”

Genitourinary/Immunotherapy/General

“Treatment strategies in human papillomavirus-related advanced penile cancer”

Authors: Mattia Longoni et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

Renal

“Immune checkpoint inhibitors plus debulking surgery for patients with metastatic renal cell carcinoma: clinical outcomes and immunological correlates of a prospective pilot trial”

Authors: Sangeeta Goswami et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

Bladder/Urothelial

“Predicting immunotherapy response of advanced bladder cancer through a meta-analysis of six independent cohorts”

Authors: Lilian Marie Boll et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“COSMIC-021 Phase Ib Study of Cabozantinib Plus Atezolizumab: Results from the Locally Advanced or Metastatic Urothelial Carcinoma Cohorts”

Authors: Sumanta Pal et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Asparagine drives immune evasion in bladder cancer via RIG-I stability and type I IFN signaling”

Authors: Wenjie Wei et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Bladder Preservation with Durvalumab plus Tremelimumab and Concurrent Radiotherapy in Patients with Localized Muscle-Invasive Bladder Cancer (IMMUNOPRESERVE): A Phase II Spanish Oncology GenitoUrinary Group Trial”

Authors: Xavier Garcia-Del-Muro et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

Prostate

“Engineering nanozyme immunomodulator with magnetic targeting effect for cascade-enzyodynamic and ultrasound-reinforced metallo-immunotherapy in prostate carcinoma”

Authors: Yandong Wang et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Predicting dose response to prostate cancer radiotherapy: validation of a radiation signature in the randomized phase III NRG/RTOG 0126 and SAKK 09/10 trials”

Authors: A Dal Pra et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models”

Authors: Patrizia Porazzi et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Validation of a digital pathology-based multimodal artificial intelligence biomarker in a prospective, real-world prostate cancer cohort treated with prostatectomy”

Authors: Anders Bjartell et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Integrating the environmental and genetic architectures of aging and mortality”

Authors: Austin Argentieri et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases”

Authors: Jonathan Mitchell et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Tumour-wide RNA splicing aberrations generate actionable public neoantigens”

Authors: Darwin Kwok et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

“Clinical and Translational Results from PORTER, a Multi-cohort Phase 1 Platform Trial of Combination Immunotherapy in Metastatic Castration-Resistant Prostate Cancer”

Authors: Matthew Galsky et al.

Dana-Farber Lank Center for GU Oncology Research Digest for the week of February 15 - 21

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