Myeloma Paper of the Day, July 2nd, suggested by Robert Orlowski
Robert Orlowski shared on X:
“Myeloma Paper of the Day: Leukocyte Ig-like receptor B family 4 (LILRB4) promotes bone lesions by inducing differentiation and maturation of osteoclasts through secreting RELT, and blocking LILRB4 signaling inhibits bone lesion formation in myeloma models.”
Source: Robert Orlowski/X
LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway
Authors: Hongying Wang, Lei Wang, Huiwen Luan, Jing Xiao, Zhiling Zhao, Pengfei Yu, Mi Deng, Yifan Liu, Shuhao Ji, Junjie Ma, Yan Zhou, Jiashen Zhang, Xianhui Meng, Juan Zhang, Xinyu Zhao, Chunling Li, Fangmin Li, Dapeng Wang, Shujuan Wei, Lijun Hui, Siman Nie, Changzhu Jin, Zhiqiang An, Ningyan Zhang, Yaopeng Wang, Cheng Cheng Zhang and Zunling Li.
Other posts featuring Robert Orlowski on OncoDaily.
Robert Orlowski holds multiple positions at The University of Texas MD Anderson Cancer Center, including Chairman, Ad Interim Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics within the Division of Cancer Medicine.
Additionally, he chairs the SWOG Barlogie/Salmon Myeloma Committee, which is part of the National Clinical Trials Network, dedicated to advancing new therapies and understanding the biology of myeloma.
