Wee Joo Chng: Presenting the Role of Superenhancers in Myeloma at the 2025 Asian Oncology Summit
Wee Joo Chng, Vice President of Biomedical Science Research at National University of Singapore, shared a post on LinkedIn:
“I am so happy to be invited to present our work on ‘The role of superenhancers in Myeloma’ at the 2025 Asian Oncology Summit in Seoul.
It is not often that I get asked to present on our science, although our group published as much (if not more) on the science and biology of Myeloma than the clinical aspect!
For those interested in the topic of Superenhancers in Blood Cancers, below are the links to papers we have published on this topic:
Title: Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma
Authors: Sinan Xiong, Jianbiao Zhou, Tze King Tan, Tae-Hoon Chung, Tuan Zea Tan, Sabrina Hui-Min Toh, Nicole Xin Ning Tang, Yunlu Jia, Yi Xiang See, Melissa Jane Fullwood, Takaomi Sanda and Wee-Joo Chng
You can read the Full Article in Nature Communications.
Title: Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma
Authors: Yunlu Jia, Jianbiao Zhou, Tze King Tan, Tae-Hoon Chung, Yongxia Chen, Jing-Yuan Chooi, Takaomi Sanda, Melissa J. Fullwood, Sinan Xiong, Sabrina H.M. Toh, Kalpnaa Balan, Regina W.J. Wong, Julia S.L. Lim, Enfan Zhang, Zhen Cai, Peng Shen, Wee Joo Chng.
You can read the Full Article in Cancer Research.
Title: Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma
Authors: Yunlu Jia, Jianbiao Zhou, Tze King Tan, Tae-Hoon Chung, Regina Wan Ju Wong, Jing-Yuan Chooi, Julia Sze Lynn Lim, Takaomi Sanda, Melissa Ooi, Sanjay De Mel, Cinnie Soekojo, Yongxia Chen, Enfan Zhang, Zhen Cai, Peng Shen, Jian Ruan, Wee-Joo Chng
You can read the Full Article in Blood Cancer Journal.
Title: Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma
Authors: Jianbiao Zhou, Sabrina Hui-Min Toh, Tze King Tan, Kalpnaa Balan, Jing Quan Lim, Tuan Zea Tan, Sinan Xiong, Yunlu Jia, Siok-Bian Ng, Yanfen Peng, Anand D. Jeyasekharan, Shuangyi Fan, Soon Thye Lim, Chin-Ann Johnny Ong, Choon Kiat Ong, Takaomi Sanda, Wee-Joo Chng
You can read the Full Article in Molecular Cancer.
Title: Super-enhancers: critical roles and therapeutic targets in hematologic malignancies
Authors: Yunlu Jia, Wee-Joo Chng, Jianbiao Zhou
You can read the Full Article in the Journal of Hematology and Oncology.
More posts featuring Wee Joo Chng.
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December 6-8, 2024
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ASCO Annual Meeting
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Yvonne Award 2024
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OncoThon 2024, Online
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Global Summit on War & Cancer 2023, Online
Dec. 14-16, 2023