Yüksel Ürün: Platinum-based chemotherapy affects immune cell composition in urothelial cancer
Yüksel Ürün shared a post on X:
“Platinum-based chemotherapy affects immune cell composition and tumor microenvironment in urothelial cancer. Increases in CD8+ T cells and PD-L1+ cells, but also fibroblast-based TGF-β signaling, may explain mixed results in clinical trials with chemo and immune checkpoint inhibitors.”
Authors: Maksim A Chelushkin, Jeroen van Dorp, Sandra van Wilpe, Iris M Seignette, Jan-Jaap J Mellema, Maartje Alkemade, Alberto Gil-Jimenez, Dennis Peters, Wim Brugman, Chantal F Stockem, Erik Hooijberg, Annegien Broeks, Bas W G van Rhijn, Laura S Mertens, Antoine G Van der Heijden, Niven Mehra, Maurits L van Montfoort, Lodewyk F A Wessels, Daniel J Vis, Michiel S Van der Heijden
Source: Yüksel Ürün/X
Yüksel Ürün is a Medical Oncology professor at Ankara University School of Medicine in Turkey. His research focuses on genitourinary cancers, covering epidemiology, diagnosis, biomarkers, meta-analysis, and treatment outcomes. His dedication to patient care and research inspires positive change in the medical field.