Francisco J Esteva shares POLAR study results on chemotherapy-induced neuropathy
Francisco J Esteva, Chief of the Division of Hematology and Medical Oncology at Lenox Hill Hospital and a Professor of Medicine at the Zucker School of Medicine, shared a post on LinkedIn:
“Chemotherapy-induced nerve damage can be tough – sometimes even forcing patients to stop treatment early. But the POLAR study offers hope.
Using hand cooling and compression, researchers cut the rate of severe chemotherapy-induced peripheral neuropathy nearly in half: from 50% to 29% with cooling, and 38% to 24% with compression. Simple strategies, big impact.
More research is needed, but these results suggest we may be closer to protecting nerves – and preserving quality of life – during taxane-based chemo.”
Title: Efficacy of Hand Cooling and Compression in Preventing Taxane-Induced Neuropathy: The POLAR Randomized Clinical Trial
Journal: JAMA Oncology
Authors: Laura L. Michel, Daniel Schwarz, Philipp Romar, Manuel Feisst, Daniel Hamberger, Anastasia Priester, Eileen Kurre, Eva Klein, Jana Müller, Timo Schinköthe, Markus Weiler, Katharina Smetanay, Carlo Fremd, Sabine Heublein, Verena Thewes, Michael O. Breckwoldt, Dirk Jäger, Martin Bendszus, Frederik Marmé, Andreas Schneeweiss
Francisco J Esteva shared findings from the POLAR study.
Study demonstrated that hand cooling and compression significantly reduced the incidence of severe chemotherapy-induced peripheral neuropathy.
He noted the potential for these strategies to preserve quality of life in patients undergoing taxane-based chemotherapy and emphasized the need for further research.
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