Science

Srinivas Viswanathan: TFE3 fusion drives a key oxidative phosphorylation in translocation RCC

Srinivas Viswanathan/dana-farber.org

Feb 8, 2025, 07:09

Srinivas Viswanathan: TFE3 fusion drives a key oxidative phosphorylation in translocation RCC

Srinivas Viswanathan, Principal Investigator at Dana-Farber Cancer Institute and an Assistant Professor at Harvard Medical School, shared an article by Jiao Li, et al. on X:

“New study! ‘

Excited to share our research on translocation RCC published in Nature Metabolism, in collaboration with Liron Bar-Peled.

We reveal how the TFE3 fusion drives a key oxidative phosphorylation (OXPHOS) metabolic program in this kidney cancer.”

Oncogenic TFE3 fusions drive OXPHOS and confer metabolic vulnerabilities in translocation renal cell carcinoma.

Authors: Jiao Li, et al.

Srinivas Viswanathan: TFE3 fusion drives a key oxidative phosphorylation in translocation RCC

cancer Dana-Farber Cancer Institute fight against cancer Global fight against cancer Harvard Medical School Jiao Li kidney cancer Liron Bar-Peled nature metabolism OncoDaily Oncology oxidative phosphorylation OXPHOS renal cell carcinoma Srinivas Viswanathan TFE3 translocation RCC

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