Nina Niu Sanford: Single fraction RT significantly improves hepatic pain can be considered standard palliative treatment

Nina Niu Sanford shared a post by Jelena Lukovic, Radiation Oncologist, Princess Margaret Cancer Centre on X, adding:

“Big congrats to Laura Dawson & team for completing this symptom-based, palliative radiotherapy RCT. 8Gy x 1 ~whole liver RT improves pain in 67% Agree that all patients fitting study criteria should be offered this simple, convenient, safe & cost-effective treatment.”

Quoting Jelena Lukovic:

“Single fraction RT (8Gy) significantly improves hepatic pain compared with best supportive care and can be considered standard palliative treatment. No increase in toxicity.”

Palliative radiotherapy versus best supportive care in patients with painful hepatic cancer (CCTG HE1): a multicentre, open-label, randomised, controlled, phase 3 study

Authors: Prof Laura A Dawson, Prof Jolie Ringash,  Alysa Fairchild,  Paul Stos,  Kristopher Dennis,  Aamer Mahmud,  Teri Lynn Stuckless, Francois Vincent,  Prof David Roberge,  Matthew Follwell, Raimond K W Wong,  Derek J Jonker,  Prof Jennifer J Knox, Prof Camilla Zimmermann,  Philip Wong,  Prof Aisling S Barry,  Marc Gaudet, Prof Rebecca K S Wong,  Thomas G Purdie,  Prof Dongsheng Tu, Christopher J O’Callaghan.

Source: Jelena Lukovic/X and Nina Niu Sanford/X

Dr. Nina Niu Sanford is an Assistant Professor and Chief of Gastrointestinal Radiation Oncology at Harvard/Brigham and Women’s Hospital/Massachusetts General Hospital. She specializes in treating gastrointestinal cancers and actively participates in clinical trials combining high-dose radiation therapy with immunotherapy. Additionally, she researches healthcare access disparities and conducts pan-cancer outcomes research using large databases.