Results suggest olanzapine should be a standard to reduce chemotherapy-induced nausea and vomiting
Kenrick Ng, Barts Health NHS Trust shared a post on X by Yüksel Ürün:
“Evidence for using olanzapine, an effective and cost friendly antiemetic, is robust but very underused in U.K.
We have also demonstrated how using olanzapine in a steroid-sparing protocol reduces rates of neutropenic sepsis in GCT patients”
Authors: Ernese Gjafa, Kenrick Ng, Tami Grunewald, Myria Galazi, Erik Skyllberg, Peter Wilson, Constantine Alifrangis, Jonathan Shamash
Quoting Yüksel Ürün’s post:
“In a phase 3 trial (Again and again…) with 560 patients, adding olanzapine to dexamethasone, palonosetron, and aprepitant increased complete response rates from 82% to 91%.
Results suggest olanzapine should be a standard to reduce chemotherapy-induced nausea and vomiting (CINV).”
Source: Kenrick Ng/X and Yüksel Ürün/X
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