Diego A. Díaz García: Subclonal Immune Evasion in NSCLC
Diego A. Díaz García, , Medical Oncologist / CEO / Founder at CánCare – Advanced Specialty in Oncology, shared on X about a recent paper shared by Krijn K. Dijkstra et al. published in Cancer Cell:
“Subclonal immune evasion in NSCLC:
Using organoid – T cell co-cultures from TRACERx, researchers show genetically distinct tumor subclones can evade immunity differently, even within the same tumor. Immune escape isn’t uniform, it’s evolutionary and clonal.”
Title: Subclonal immune evasion in non-small cell lung cancer
Authors: Krijn K. Dijkstra, Roberto Vendramin, Despoina Karagianni, Maartje Witsen, Felipe Gálvez-Cancino, Mark S. Hill, Kane A. Foster, Vittorio Barbè, Mihaela Angelova, Robert E. Hynds, David R. Pearce, Carlos Martínez-Ruiz, James R.M. Black, Ariana Huebner, Oriol Pich, Andrew Rowan, Marcellus Augustine, Clare Puttick, David A. Moore, Lydia L. Liu, Sadegh Saghafinia, Joris van de Haar, Selvaraju Veeriah, Cristina Naceur-Lombardelli, Antonia Toncheva, Supreet Kaur Bola, Crispin T. Hiley, Mariam Jamal-Hanjani, Nicholas McGranahan, Kevin Litchfield, James L. Reading, Benny Chain
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