Transition metal complexes as an approach for targeting emerging cancer hallmarks – The Babak Lab
The Babak Lab shared a post on LinkedIn:
“Scientific Wednesday։ Transition metal complexes as an approach for targeting emerging cancer hallmarks
Over the past decade, our understanding of cancer’s complexity has deepened significantly. Research has unveiled how cancer cells acquire specific hallmarks to transform into malignant cells. For today’s Scientific Wednesday post, we would like to invite our readers to have a read of our review, published in 2022. This article sheds light on innovative strategies for targeting cancer stem cells (CSCs) and the tumor microbiome using transition metal complexes.
Key takeaways:
• Phenotypic plasticity drives cancer cell invasion and metastasis.
• Epigenetic reprogramming regulates nonmutational changes influencing cell states.
• Transition metals are pivotal in the tumor microenvironment (TME), impacting cancer progression and treatment response.
• Microbiome interactions with transition metals unveil potential for innovative therapies.
To find out more about which transition metal complexes were found to deplete cancer stem cells (CSCs), access the article using the following link.”
Authors: Meng Rui Chang et al.
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