Peter Adams: Aged tissues at increased risk of cancer due to “precarious balance”

Peter Adams, Director of NCI-designated Cancer Genome and Epigenetics Program at Sanford Burnham Prebys (SBP), shared on X a recent paper by Aaron Havas et al. titled “Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer” published in BioRxiv.

Authors: Aaron Havas, Kathryn Lande, Adarsh Rajesh, Garrett Evensen, Siva Karthik Varanasi, Linshan Shang, Elizabeth Schmidt, Jin Lee, Kenneth Kim, ProfileMarcos Garcia Teneche, Filipe Hoffmann, Peter Adams et al.

“New study led by talented post doc in the lab Aaron Havas:

1. aged tissues at increased risk of cancer due to ‘precarious balance’.
2. age-activated IFN signaling is an adaptive response to prevent cancer in older tissues, but with maladaptive consequence.”

Source: Peter Adams/X