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After TKI , adding Pembro to chemo DOES NOT improve OS – Rami Manochakian
Jun 7, 2023, 10:31

After TKI , adding Pembro to chemo DOES NOT improve OS – Rami Manochakian

NEGATIVE results of Keynote789 trial:

Platinum + Pem +/- Pembro for TKI-resistant EGFR mutant NSCLC

❌PFS HR 0.8, P=0.0122
mPFS: 5.6 vs 5.5 mths

❌OS HR 0.84, P=0.0362
mOS: 15.9 vs 14.7 mths

After TKI , adding Pembro to chemo DOES NOT improve OS

Source: Rami Manochakian / Twitter